Penis

TNM 7 Classification

TNM 6 Classification

1. Rules for Classification

The classification applies only to carcinomas. There should be histological confirmation of the disease.

The following are the procedures for assessing T, N, and M categories:

T categories. Physical examination and endoscopy
N categories. Physical examination and imaging
M categories. Physical examination and imaging

2. Anatomical Subsites

1. Prepuce (C60.0)
2. Glans penis (C60.1)
3. Body of penis (C60.2)

3. Regional Lymph Nodes

The regional lymph nodes are the superficial and deep inguinal and the pelvic nodes.

4. TNM Clinical Classification

4.1. T - Primary Tumour

TX. Primary tumour cannot be assessed
T0. No evidence of primary tumour
Tis. Carcinoma in situ
Ta. Noninvasive verrucous carcinoma
T1. Tumour invades subepithelial connective tissue
T2. Tumour invades corpus spongiosum or cavernosum
T3. Tumour invades urethra or prostate
T4. Tumour invades other adjacent structures

4.2. N - Regional Lymph Nodes

NX. Regional lymph nodes cannot be assessed
N0. No regional lymph node metastasis
N1. Metastasis in a single superficial inguinal lymph node
N2. Metastasis in multiple or bilateral superficial inguinal lymph nodes
N3. Metastasis in deep inguinal or pelvic lymph node(s), unilateral or bilateral

4.3. M - Distant Metastasis

MX. Distant metastasis cannot be assessed
M0. No distant metastasis
M1. Distant metastasis

5. pTNM Pathological Classification

The pT, pN, and pM categories correspond to the T, N, and M categories.

6. G Histopathological Grading

GX. Grade of differentiation cannot be assessed
G1. Well differentiated
G2. Moderately differentiated
G3-4. Poorly differentiated/undifferentiated

7. Stage Grouping

Stage 0 Tis N0 M0 Ta N0 M0 Stage I T1 N0 M0 Stage II T1 N1 M0 T2 N0, N1 M0 Stage III T1. T2 N2 M0 T3 N0, N1, N2 M0 Stage IV T4 Any N M0 Any T N3 M0 Any T Any N M1

8. Summary

Penis Tis In situ Ta Noninvasive verrucous carcinoma T1 Subepithelial connective tissue T2 Corpus spongiosum, cavernosum T3 Urethra, prostate T4 Other adjacent structures N1 One superficial inguinal N2 Multiple or bilateral superficial inguinal N3 Deep inguinal or pelvic